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KMID : 1103720120660020149
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Journal of the Korean Society of Radiology
2012 Volume.66 No. 2 p.149 ~ p.153
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Radiologic Findings of Immunoglobulin G4 Related Sclerosing Esophagitis: A Case Report
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Kim Mi-Sun
Kim Su-Young
Lee Byung-Hoon
Hwang Yoon-Joon
Han Yoon-Hee
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Abstract
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We describe a case of immunoglobulin G4 (IgG4)-related sclerosing esophagitis occurring in a 63-year-old man with progressive dysphagia and 10-kg weight loss over 9 months. An esophagoscopy revealed significant stricture with diffuse mucosal friability and ulceration at mid esophagus level. Barium esophagogram showed diffuse stenosis at the mid and lower esophagus levels with ulcerations and irregularity of the mucosa. Multidetector computed tomography revealed diffuse edematous and circumferential thickening of the submucosa and muscle layer of this esophageal segment. Fluorine 18 fluorodeoxyglucose positron emission tomography (FDG PET) revealed diffuse mild FDG uptake in mid to lower esophagus. Although benign inflammatory lesion was suspected based on the imaging findings, the patient underwent surgery for worsening esophageal stricture and the esophageal lesion was pathologically confirmed as IgG4-related sclerosing esophagitis. Radiologic benignancy and high clinical suspicion for IgG4-related sclerosing disease may help making a proper decision and avoiding unnecessary operation.
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KEYWORD
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IgG4, FDG PET-CT, Immunoglobulin G4, Fluorodeoxyglucose
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